Pharmocology editor

[RJohann]

I have created a modified drug list and renamed it "modified drug list". How do I make it the active list instead of HPS using the "default"?

[Pete Dickens]

Hej RJohann,

Help from a fellow techinician.

Open your HPS software.
Click HPS > HPS Drug Responses > Modify System Drug Responses and browse to your newly created drug list (you probably know this bit, however)

The next time you open the HPS software it will use the last drug list that you told it to, so providing you browsed to the right file, that list is now default.

Hope thats some help answering your question, I'd be happy for your boss to pay for me to come show you, its raining here...

PETE

[El Medic]

I have several METI products. One of them being a HPS. I have the Editor installed on the Apple desktop, but would like to put the software on one of my many mac books. Is this software available on one of the install disk that I currently have? :cool:

[redroc]

not sure about the legalities of doing this. The install disk has a windoze and mac install but usually you are only licensed to install on one machine. I would call Customer Support to see if you are entitled to the disk.

[El Medic]

Well I finally got a hold of a METI support person that could help. He supplied me with the disc with the software. It has both PC and Mac based version of the editor along with the user guide. Very helpful and also totally fine to put on all the computers that you want to use.

[haime]

hi every one regarding the pharmacology editor how they make the conversion? we try to administered epinephrine of 1000mcg which is 1mg it will give too much effect to istan and ecs and hps simulator.for istan from HR of 71 become 181 it is impossible that effect anyone can give me some details how they make the conversion thank you.

[Pete Dickens]

Hallo Haime,

how are you administering the adrenaline? IV or IM? 1mg of adrenaline IV introduced to an awake patient will have very profound cardiovascular effects, and this could induce extremely high heart rates possibly as high as those you are seeing.

Also, bear in mind that the waveform is merely part of the simulation and not really an analytical tool, (for example it "measures" VFib as 151 BPM), so its best not to rely on it for data

It is possible to alter the dose-response curve for epinephrine using the pharmacology drug editor, although I've not heard of anyone having to, you would need data from published papers available through PubMed for example

[haime]

HI MR. PETE

i appreciate someone reply,We gave 1000mcg through bolus, its not specified in the software either it is IV or IM but its understood that bolus is given for IV. and we are not given ADRENALIN through IM it can administer through IV,IO,IC that is base on my experience. the question here is why this dose can kill the simulator px waveform will flatline within or more or less than 1 minute which is not usual for real PX. there is no maximum dose for adrenalin usually interval every 3minutes can administer, i made something for it i changed the mcg to mg through pharmacology editor to see the effect,the good point when we give 1mg bolus adrenaline almost no effect which is normal for real px. so the main question here is why the unit dose between mcg and mg conversion is not giving the same effect. as we know that 1000mcg is 1mg. thank you and hope you can give more details.

[Pete Dickens]

Haime,

I'd be interested to look at your logs. And it would be worth double checking with one of your clinicians as to the effect of a 1mg bolus of IV Adrenaline/Epinephrine. I don't agree that a 1mg bolus IV would give almost no effect to a normal patient

Anyone else here want to chip in?

[haime]

Mr.Pete,

ok ill send you the logs its better to show you and check it for me. thanks.

[haime]

mr. pete,

can you send me your email pls. so i can send you the logs thanks.

[Pete Dickens]

Hi Haime, sorry for the delay, work gets in the way from time to time

peter.dickens@bristol.ac.uk

http://www.aims-cetl.co.uk/

[haime]

mr. pete,

i just want to clarify that the scenario we played is anaphelaxix case we try to administered the 1000 mcg of adrenaline will stop the simulator or it will kill the manikin in a seconds only some of our clinician said it might be tachy but not kill the simulator immediately.and i think that there is a problem with the unit it was mcg before but we play the phrama editor and we changed the mcg to mg. my quesition is if they change the mcg to mg in the pharma editor will change the effect of the drugs? 1mg is no effect but 1000mcg more effect.thank u

[AFmedic]

From METI I was told that if you give only 100 mcg it will give you the appropriate response that would hope to see from 1mg of epi. I've gone as far as to go into the pharm editor and change the concentration of the injectate to 10 mcg so that when a full 10 ml's are given (our hospital uses a 100 mcg per ml prefilled), that they will actually see a more realistic response. As mentioned above, if I was to give my HPS 1000 mcg of epi, he would very quicky bottom out his isch idx and throw himself into vfib. Hope this helps.

-Ivan

[rshotto]

Haime,

A little back ground on the Epinephrine dosage. The Epi is in the system in mcg because that is typically what anesthesiologists use for administration. If you change only the concentration of the Epi from mcg to mg and don't change the Base, Clinical and Compartment sets, along with the pharmacodynamics, the drug will probably not work properly either. METI has under took the task of adding an EPI dose in mg, with the correct data input so the drug will react apporpriately. Please feel free to contact the Education & Training team here at METI.

Warm Regards,

Rob shotto

[AETraining]

Any update on the Epi Dose correction to mg?